| ADP | Player | Tier | Bye Week | Years Pro | Salary | Points | Madden | Injury |
| 44.00 | QB Justin Fields | QB | 13 | 2 | $7,790,000 | 0 | 74/100 | 91/100 |
| 45.00 | QB Justin Herbert | QB | 5 | 3 | $2,000,000 | 0 | 88/100 | 93/100 |
| 48.00 | RB Dameon Pierce | RB | 7 | 1 | $3,700,000 | 0 | 72/100 | 93/100 |
| 54.00 | TE Darren Waller | TE | 13 | 7 | $27,800,000 | 0 | 91/100 | 90/100 |
| 56.00 | QB Trevor Lawrence | QB | 9 | 2 | $12,670,000 | 0 | 76/100 | 92/100 |
| 58.00 | TE Kyle Pitts | TE | 11 | 2 | $11,630,000 | 0 | 87/100 | 92/100 |
| 62.00 | RB James Conner | RB | 14 | 6 | $7,470,000 | 0 | 81/100 | 85/100 |
| 63.00 | RB Rachaad White | RB | 5 | 1 | $4,210,000 | 0 | 70/100 | 90/100 |
| 65.00 | RB Alexander Mattison | RB | 13 | 4 | $2,650,000 | 0 | 77/100 | 90/100 |
| 73.00 | WR Mike Evans | WR | 5 | 9 | $15,620,000 | 0 | 92/100 | 95/100 |
| 74.00 | WR Tyler Lockett | WR | 5 | 8 | $47,700,000 | 0 | 90/100 | 96/100 |
| 75.00 | WR Christian Kirk | WR | 9 | 5 | $52,000,000 | 0 | 81/100 | 89/100 |
| 80.00 | WR Michael Pittman Jr. | WR | 11 | 0 | TBD | TBD | ||
| 83.00 | WR Marquise Brown | WR | 14 | 4 | $13,910,000 | 0 | 84/100 | 88/100 |