Rankings Updated: Thursday, December 3, 2020 @ 1:15 PM EST
| Rank | Player | Points | Opp. | Game Time | Status |
| 1 | RB Dalvin Cook | + 22 | vs JAC | Sunday 1:00 PM | Limited Practice On Wednesday. Questionable For Week 13 Vs. Jacksonville (Ankle) |
| 2 | RB Derrick Henry | + 17 | vs CLE | Sunday 1:00 PM | |
| 3 | RB James Robinson | + 17 | @ MIN | Sunday 1:00 PM | |
| 4 | RB Aaron Jones | + 16 | vs PHI | Sunday 8:20 PM | |
| 5 | RB Nick Chubb | + 14 | @ TEN | Sunday 1:00 PM | |
| 6 | RB Austin Ekeler | + 17 | vs NE | Sunday 4:25 PM | |
| 7 | RB David Montgomery | + 14 | vs DET | Sunday 1:00 PM | |
| 8 | RB Raheem Mostert | + 13 | vs BUF | Monday 8:15 PM | |
| 9 | RB Ezekiel Elliott | + 13 | @ BAL | Thursday 4:30 PM | |
| 10 | RB Miles Sanders | + 14 | @ GB | Sunday 4:25 PM | |
| 11 | RB Alvin Kamara | + 14 | @ ATL | Sunday 1:00 PM | Limited Practice On Wednesday. Questionable For Week 13 At Atlanta (Foot) |
| 12 | RB Chris Carson | + 14 | vs NYG | Sunday 4:05 PM | |
| 13 | RB Antonio Gibson | + 13 | @ PIT | Sunday 1:00 PM | |
| 14 | RB D'Andre Swift | + 15 | @ CHI | Thursday 12:30 PM | Limited Practice On Wednesday. Questionable For Week 13 At Chicago (Concussion) |
| 15 | RB Wayne Gallman | + 12 | @ SEA | Sunday 4:05 PM | |
| 16 | RB Kenyan Drake | + 11 | vs LAR | Sunday 4:05 PM | |
| 17 | RB Clyde Edwards-Helaire | + 13 | vs DEN | Thursday 8:20 PM | |
| 18 | RB Jonathan Taylor | + 12 | @ HOU | Sunday 1:00 PM | |
| 19 | RB Damien Harris | + 10 | @ LAC | Sunday 1:00 PM | |
| 20 | RB JK Dobbins | + 12 | vs DAL | Thursday 8:20 PM | Ir. Reserve - Covid-19 (Illness) |
| 21 | RB Frank Gore | + 11 | vs LV | Sunday 1:00 PM | |
| 22 | RB Melvin Gordon | + 11 | @ KC | Sunday 4:05 PM | |
| 23 | RB Kareem Hunt | + 12 | @ TEN | Sunday 1:00 PM | Limited Practice On Wednesday. Questionable For Week 13 At Tennessee (Thigh) |
| 24 | RB Giovani Bernard | + 12 | @ MIA | Sunday 1:00 PM | |
| 25 | RB Devontae Booker | + 10 | @ NYJ | Sunday 1:00 PM | |
| 26 | RB Josh Jacobs | + 10 | @ NYJ | Sunday 1:00 PM | Questionable For Week 13 At N.y. Jets (Ankle) |
| 27 | RB Benny Snell Jr | + 8 | vs WAS | Thursday 8:20 PM | |
| 28 | RB Nyheim Hines | + 12 | @ HOU | Sunday 1:00 PM | |
| 29 | RB Todd Gurley | + 9 | vs NO | Sunday 1:00 PM | Questionable For Week 13 Vs. New Orleans (Knee) |
| 30 | RB Duke Johnson | + 10 | vs IND | Sunday 1:00 PM | |
| 31 | RB Zack Moss | + 8 | @ SF | Sunday 1:00 PM | |
| 32 | RB Darrell Henderson | + 8 | @ ARI | Sunday 4:05 PM | |
| 33 | RB Latavius Murray | + 8 | @ ATL | Sunday 1:00 PM | |
| 34 | RB Chase Edmonds | + 9 | vs LAR | Sunday 4:05 PM | |
| 35 | RB James White | + 10 | @ LAC | Sunday 1:00 PM | |
| 36 | RB James Conner | + 8 | vs WAS | Thursday 8:20 PM | Ir. Reserve - Covid-19 (Illness) |
| 37 | RB Devin Singletary | + 9 | @ SF | Sunday 1:00 PM | |
| 38 | RB Jamaal Williams | + 8 | vs PHI | Sunday 8:20 PM | |
| 39 | RB J.D. McKissic | + 9 | @ PIT | Sunday 1:00 PM | |
| 40 | RB Malcolm Brown | + 6 | @ ARI | Sunday 4:05 PM | |
| 41 | RB Brian Hill | + 6 | vs NO | Sunday 1:00 PM | |
| 42 | RB Cam Akers | + 6 | @ ARI | Sunday 4:05 PM | |
| 43 | RB Jerick McKinnon | + 7 | vs BUF | Monday 8:15 PM | |
| 44 | RB Tony Pollard | + 6 | @ BAL | Thursday 4:30 PM | |
| 45 | RB Carlos Hyde | + 7 | vs NYG | Sunday 4:05 PM | |
| 46 | RB Kalen Ballage | + 7 | vs NE | Sunday 4:25 PM | Limited Practice On Wednesday. Questionable For Week 13 Vs. Las Vegas (Ankle) |
| 47 | RB Joshua Kelley | + 4 | vs NE | Sunday 4:25 PM | |
| 48 | RB Jordan Wilkins | + 4 | @ HOU | Sunday 1:00 PM | |
| 49 | RB Matt Breida | + 5 | vs CIN | Sunday 1:00 PM | |
| 50 | RB Mark Ingram | + 5 | vs DAL | Thursday 8:20 PM | Ir. Reserve - Covid-19 (Illness) |
| 51 | RB David Johnson | + 6 | vs IND | Sunday 1:00 PM | Ir. Injured Reserve. Expected Return - Week 13 (Concussion) |
| 52 | RB Adrian Peterson | + 5 | @ CHI | Thursday 12:30 PM | |
| 53 | RB Phillip Lindsay | + 5 | @ KC | Sunday 4:05 PM | Did Not Practice On Wednesday. Questionable For Week 13 At Kansas City (Knee) |
| 54 | RB Le'Veon Bell | + 6 | vs DEN | Thursday 8:20 PM | |
| 55 | RB DeAndre Washington | + 5 | vs CIN | Sunday 1:00 PM | Did Not Practice On Wednesday. Questionable For Week 13 Vs. Cincinnati (Hamstring) |
| 56 | RB Ito Smith | + 5 | vs NO | Sunday 1:00 PM | |
| 57 | RB Gus Edwards | + 5 | vs DAL | Thursday 8:20 PM | |
| 58 | RB Alexander Mattison | + 5 | vs JAC | Sunday 1:00 PM | |
| 59 | RB Boston Scott | + 6 | @ GB | Sunday 4:25 PM | |
| 60 | RB Salvon Ahmed | + 5 | vs CIN | Sunday 1:00 PM | Limited Practice On Wednesday. Questionable For Week 13 Vs. Cincinnati (Shoulder) |
| 61 | RB Myles Gaskin | + 6 | vs CIN | Sunday 1:00 PM | Ir. Injured Reserve. Expected Return - Week 13 (Knee - Mcl) |
| 62 | RB Jeff Wilson | + 3 | vs BUF | Monday 8:15 PM | |
| 63 | RB Kerryon Johnson | + 4 | @ CHI | Thursday 12:30 PM | |
| 64 | RB Royce Freeman | + 4 | @ KC | Sunday 4:05 PM | |
| 65 | RB Jalen Richard | + 4 | @ NYJ | Sunday 1:00 PM | |
| 66 | RB Tevin Coleman | + 4 | vs BUF | Monday 8:15 PM | Questionable For Week 13 Vs. Buffalo (Knee) |
| 67 | RB Anthony McFarland Jr | + 4 | vs WAS | Thursday 8:20 PM | |
| 68 | RB Samaje Perine | + 3 | @ MIA | Sunday 1:00 PM | |
| 69 | RB Devonta Freeman | + 4 | @ SEA | Sunday 4:05 PM | Ir. Injured Reserve. Expected Return - Week 13 (Ankle) |
| 70 | RB Peyton Barber | + 2 | @ PIT | Sunday 1:00 PM | |
| 71 | RB Kyle Juszczyk | + 3 | vs BUF | Monday 8:15 PM | |
| 72 | RB Ty Johnson | + 3 | vs LV | Sunday 1:00 PM | |
| 73 | RB Sony Michel | + 3 | @ LAC | Sunday 1:00 PM | |
| 74 | RB Malcolm Perry | + 3 | vs CIN | Sunday 1:00 PM | Did Not Practice On Wednesday. Questionable For Week 13 Vs. Cincinnati (Chest) |
| 75 | RB C.J. Prosise | + 2 | vs IND | Sunday 1:00 PM | Questionable For Week 13 Vs. Indianapolis (Illness) |
| 76 | RB D'Onta Foreman | + 2 | vs CLE | Sunday 1:00 PM | Did Not Practice On Wednesday. Questionable For Week 13 Vs. Cleveland (Knee) |
| 77 | RB Alfred Morris | + 2 | @ SEA | Sunday 4:05 PM | |
| 78 | RB Anthony Sherman | + 1 | vs DEN | Thursday 8:20 PM | |
| 79 | RB Travis Homer | + 2 | vs NYG | Sunday 4:05 PM | Questionable For Week 13 Vs. N.y. Giants (Knee) |
| 80 | RB T.J. Yeldon | + 2 | @ SF | Sunday 1:00 PM | |
| 81 | RB Ameer Abdullah | + 1 | vs JAC | Sunday 1:00 PM | |
| 82 | RB Corey Clement | + 1 | @ GB | Sunday 4:25 PM | |
| 83 | RB Darwin Thompson | + 1 | vs DEN | Thursday 8:20 PM | |
| 84 | RB Lamar Miller | + 1 | vs DET | Sunday 1:00 PM | |
| 85 | RB Mike Boone | + 1 | vs JAC | Sunday 1:00 PM | |
| 86 | RB Dion Lewis | + 3 | @ SEA | Sunday 4:05 PM | |
| 87 | RB Ryan Nall | + 2 | vs DET | Sunday 1:00 PM | |
| 88 | RB Dontrell Hilliard | + 2 | @ TEN | Sunday 1:00 PM | |
| 89 | RB Dexter Williams | + 1 | vs PHI | Sunday 8:20 PM | |
| 90 | RB Jeremy McNichols | + 2 | vs CLE | Sunday 1:00 PM | |
| 91 | RB Troymaine Pope | + 1 | vs NE | Sunday 4:25 PM | |
| 92 | RB Devine Ozigbo | + 2 | @ MIN | Sunday 1:00 PM | |
| 93 | RB Josh Adams | + 2 | vs LV | Sunday 1:00 PM | |
| 94 | RB Alec Ingold | + 1 | @ NYJ | Sunday 1:00 PM | Questionable For Week 13 At N.y. Jets (Ribs) |
| 95 | RB Tyler Ervin | + 2 | vs PHI | Sunday 8:20 PM | Limited Practice On Wednesday. Questionable For Week 13 Vs. Philadelphia (Ribs) |
| 96 | RB DeeJay Dallas | + 2 | vs NYG | Sunday 4:05 PM | |
| 97 | RB Patrick Laird | + 2 | vs CIN | Sunday 1:00 PM | |
| 98 | RB Darrel Williams | + 2 | vs DEN | Thursday 8:20 PM | |
| 99 | RB Eno Benjamin | + 2 | vs LAR | Sunday 4:05 PM | |
| 100 | RB Trayveon Williams | + 1 | @ MIA | Sunday 1:00 PM | |
| 101 | RB Jakob Johnson | + 1 | @ LAC | Sunday 1:00 PM | |
| 102 | RB JJ Taylor | + 1 | @ LAC | Sunday 1:00 PM | Limited Practice On Wednesday. Questionable For Week 13 At L.a. Chargers (Quadriceps) |
| 103 | RB Artavis Pierce | + 1 | vs DET | Sunday 1:00 PM | |
| 104 | RB Mike Weber | + 1 | vs PHI | Sunday 8:20 PM | |
| 105 | RB Johnny Stanton | + 1 | @ TEN | Sunday 1:00 PM | |
| 106 | RB Dare Ogunbowale | + 1 | @ MIN | Sunday 1:00 PM | Questionable For Week 13 At Minnesota (Hand) |
| 107 | RB Qadree Ollison | + 0 | vs NO | Sunday 1:00 PM | |
| 108 | RB C.J. Ham | + 1 | vs JAC | Sunday 1:00 PM | |
| 109 | RB Ty Montgomery | + 1 | @ ATL | Sunday 1:00 PM | Did Not Practice On Wednesday. Questionable For Week 13 At Atlanta (Hamstring) |
| 110 | RB Patrick Ricard | + 1 | vs DAL | Thursday 8:20 PM | Ir. Reserve - Covid-19 (Undisclosed) |
| 111 | RB Justice Hill | + 1 | vs DAL | Thursday 8:20 PM | |
| 112 | RB Jaylen Samuels | + 1 | vs WAS | Thursday 8:20 PM | Inactive For Week 12 Vs. Baltimore (Quadriceps) |
| 113 | RB Dwayne Washington | + 0 | @ ATL | Sunday 1:00 PM | |
| 114 | RB Michael Burton | + 0 | @ ATL | Sunday 1:00 PM | |
| 115 | RB Khari Blasingame | + 0 | vs CLE | Sunday 1:00 PM | |
| 116 | RB Nick Bellore | + 0 | vs NYG | Sunday 4:05 PM | |
| 117 | RB D'Ernest Johnson | + 1 | @ TEN | Sunday 1:00 PM | |
| 118 | RB Keith Smith | + 0 | vs NO | Sunday 1:00 PM | |
| 119 | RB Derek Watt | + 0 | vs WAS | Thursday 8:20 PM | |
| 120 | RB Buddy Howell | + 0 | vs IND | Sunday 1:00 PM | |
| 121 | RB Taiwan Jones | + 0 | @ SF | Sunday 1:00 PM | |
| 122 | RB Cullen Gillaspia | + 0 | vs IND | Sunday 1:00 PM | Questionable For Week 13 Vs. Indianapolis (Back) |
| 123 | RB AJ Dillon | + 1 | vs PHI | Sunday 8:20 PM | Ir. Reserve - Covid-19 (Illness) |
| 124 | WR Lynn Bowden Jr | + 1 | vs CIN | Sunday 1:00 PM | |
| 125 | RB Bryce Love | + 0 | @ PIT | Sunday 1:00 PM | Ir. Injured Reserve (Knee) |
| 126 | RB Jason Huntley | + 0 | @ GB | Sunday 4:25 PM | |
| 127 | RB Andy Janovich | + 0 | @ TEN | Sunday 1:00 PM | |
| 128 | RB Wendell Smallwood | + 0 | vs WAS | Thursday 8:20 PM | |
| 129 | RB Elijhaa Penny | + 0 | @ SEA | Sunday 4:05 PM | |
| 130 | RB Xavier Jones | + 0 | @ ARI | Sunday 4:05 PM | |
| 131 | RB Nathan Cottrell | + 0 | @ MIN | Sunday 1:00 PM | |
| 132 | RB Jonathan Williams | + 0 | @ CHI | Thursday 12:30 PM | |
| 133 | RB Gabe Nabers | + 0 | vs NE | Sunday 4:25 PM | |
| 134 | RB Austin Walter | + 0 | vs BUF | Monday 8:15 PM |