| ADP | Player | Tier | Bye Week | Years Pro | Salary | Points | Madden | Injury |
| 57.00 | RB Alvin Kamara | RB | 11 | 6 | $48,920,000 | 0 | 90/100 | 93/100 |
| 60.00 | TE Dallas Goedert | TE | 10 | 5 | $31,640,000 | 0 | 85/100 | 89/100 |
| 64.00 | RB Dalvin Cook | RB | 7 | 6 | $38,700,000 | 0 | 94/100 | 84/100 |
| 68.00 | RB D'Andre Swift | RB | 10 | 3 | $3,390,000 | 0 | 80/100 | 86/100 |
| 70.00 | RB Isiah Pacheco | RB | 10 | 1 | $3,720,000 | 0 | 64/100 | 92/100 |
| 71.00 | QB Deshaun Watson | QB | 5 | 6 | $185,000,000 | 0 | 84/100 | 89/100 |
| 76.00 | RB Javonte Williams | RB | 9 | 2 | $5,060,000 | 0 | 82/100 | 90/100 |
| 77.00 | TE Evan Engram | TE | 9 | 6 | $5,970,000 | 0 | 81/100 | 87/100 |
| 78.00 | RB James Cook | RB | 13 | 1 | $4,430,000 | 0 | 75/100 | 88/100 |
| 81.00 | WR George Pickens | WR | 6 | 1 | $4,670,000 | 0 | 74/100 | 85/100 |
| 84.00 | RB David Montgomery | RB | 9 | 4 | $4,820,000 | 0 | 84/100 | 87/100 |
| 88.00 | WR Jaxon Smith-Njigba | WR | 5 | 0 | TBD | TBD | ||
| 89.00 | RB AJ Dillon | RB | 6 | 0 | TBD | TBD | ||
| 91.00 | TE Pat Freiermuth | TE | 6 | 2 | $4,280,000 | 0 | 79/100 | 91/100 |
| 92.00 | WR Jordan Addison | WR | 13 | 0 | TBD | TBD | ||
| 93.00 | WR Jahan Dotson | WR | 14 | 1 | $6,930,000 | 0 | 75/100 | 90/100 |
| 94.00 | WR Brandin Cooks | WR | 7 | 9 | $37,470,000 | 0 | 87/100 | 90/100 |
| 95.00 | WR Treylon Burks | WR | 7 | 1 | $6,730,000 | 0 | 73/100 | 88/100 |
| 97.00 | WR Michael Thomas | WR | 11 | 7 | $41,240,000 | 0 | 90/100 | 87/100 |
| 101.00 | WR JuJu Smith-Schuster | WR | 11 | 6 | $500,000 | 0 | 80/100 | 86/100 |
| 104.00 | WR Courtland Sutton | WR | 9 | 5 | $45,690,000 | 0 | 84/100 | 86/100 |
| 105.00 | WR Gabe Davis | WR | 13 | 0 | TBD | TBD | ||
| 108.00 | RB Antonio Gibson | RB | 14 | 3 | $3,780,000 | 0 | 80/100 | 91/100 |
| 116.00 | QB Daniel Jones | QB | 13 | 4 | $2,000,000 | 0 | 70/100 | 85/100 |
| 143.00 | WR Elijah Moore | WR | 5 | 2 | $5,060,000 | 0 | 79/100 | 86/100 |