Rankings Updated: Monday, May 3, 2021 @ 10:26 AM EST
| Rank | Player | Points | Opp. | Game Time | Status |
| 1 | QB Lamar Jackson | + 24 | @ CIN | Sunday 1:00 PM | |
| 2 | QB Deshaun Watson | + 23 | vs TEN | Sunday 1:00 PM | |
| 3 | QB Aaron Rodgers | + 22 | @ CHI | Sunday 8:20 PM | |
| 4 | QB Ryan Tannehill | + 21 | @ HOU | Sunday 1:00 PM | |
| 5 | QB Tom Brady | + 21 | vs ATL | Sunday 4:25 PM | |
| 6 | QB Kirk Cousins | + 20 | @ DET | Sunday 1:00 PM | |
| 7 | QB Justin Herbert | + 20 | @ KC | Sunday 4:25 PM | |
| 8 | QB Russell Wilson | + 20 | @ SF | Sunday 4:05 PM | |
| 9 | QB Kyler Murray | + 20 | @ LAR | Sunday 4:05 PM | |
| 10 | QB Jalen Hurts | + 19 | vs WAS | Monday 8:15 PM | |
| 11 | QB Philip Rivers | + 18 | vs JAC | Sunday 1:00 PM | |
| 12 | QB Matt Ryan | + 17 | @ TB | Sunday 1:00 PM | |
| 13 | QB Andy Dalton | + 17 | @ NYG | Thursday 4:30 PM | |
| 14 | QB Drew Brees | + 17 | @ CAR | Sunday 1:00 PM | |
| 15 | QB Mitchell Trubisky | + 17 | vs GB | Sunday 1:00 PM | |
| 16 | QB Derek Carr | + 17 | @ DEN | Sunday 8:20 PM | |
| 17 | QB Matthew Stafford | + 17 | vs MIN | Thursday 12:30 PM | Limited Practice On Friday. Questionable For Week 17 Vs. Minnesota (Ankle) |
| 18 | QB Drew Lock | + 17 | vs LV | Sunday 4:05 PM | |
| 19 | QB Baker Mayfield | + 16 | vs PIT | Sunday 1:00 PM | |
| 20 | QB Cam Newton | + 16 | vs NYJ | Sunday 1:00 PM | |
| 21 | QB Teddy Bridgewater | + 16 | vs NO | Sunday 1:00 PM | |
| 22 | QB Josh Allen | + 15 | vs MIA | Sunday 1:00 PM | |
| 23 | QB Daniel Jones | + 15 | vs DAL | Sunday 1:00 PM | |
| 24 | QB Tua Tagovailoa | + 15 | @ BUF | Sunday 1:00 PM | |
| 25 | QB Alex Smith | + 14 | @ PHI | Sunday 1:00 PM | Limited Practice On Friday. Questionable For Week 17 At Philadelphia (Calf) |
| 26 | QB Chad Henne | + 14 | vs LAC | Thursday 8:20 PM | |
| 27 | QB Sam Darnold | + 14 | @ NE | Sunday 1:00 PM | |
| 28 | QB C.J. Beathard | + 14 | vs SEA | Monday 8:15 PM | |
| 29 | QB John Wolford | + 14 | vs ARI | Sunday 4:05 PM | |
| 30 | QB Mike Glennon | + 13 | @ IND | Sunday 1:00 PM | |
| 31 | QB Mason Rudolph | + 13 | @ CLE | Monday 5:00 PM | |
| 32 | QB Brandon Allen | + 12 | vs BAL | Sunday 1:00 PM | |
| 33 | QB Taysom Hill | + 6 | @ CAR | Sunday 1:00 PM | |
| 34 | QB Matt Barkley | + 5 | vs MIA | Sunday 1:00 PM | |
| 35 | QB Chase Daniel | + 2 | vs MIN | Thursday 12:30 PM | |
| 36 | QB Gardner Minshew | + 1 | @ IND | Sunday 1:00 PM | |
| 37 | QB Jarrett Stidham | + 1 | vs NYJ | Sunday 1:00 PM | |
| 38 | QB Blaine Gabbert | + 1 | vs ATL | Sunday 4:25 PM | |
| 39 | QB Jacoby Brissett | + 0 | vs JAC | Sunday 1:00 PM | |
| 40 | QB Taylor Heinicke | + 0 | @ PHI | Sunday 1:00 PM | |
| 41 | QB Nick Foles | + 0 | vs GB | Sunday 1:00 PM | |
| 42 | QB Colt McCoy | + 0 | vs DAL | Sunday 1:00 PM | |
| 43 | QB Steven Montez | + 0 | @ PHI | Sunday 1:00 PM | |
| 44 | QB Marcus Mariota | + 0 | @ DEN | Sunday 8:20 PM | |
| 45 | QB Joshua Dobbs | + 0 | @ CLE | Monday 5:00 PM | |
| 46 | QB Tyrod Taylor | + 0 | @ KC | Sunday 4:25 PM | |
| 47 | QB Jameis Winston | + 0 | @ CAR | Sunday 1:00 PM | |
| 48 | QB Garrett Gilbert | + 0 | @ NYG | Thursday 4:30 PM | |
| 49 | QB Phillip Walker | + 0 | vs NO | Sunday 1:00 PM | |
| 50 | QB Ryan Finley | + 0 | vs BAL | Sunday 1:00 PM | |
| 51 | QB Josh Rosen | + 0 | vs SEA | Monday 8:15 PM | |
| 52 | QB Matt Schaub | + 0 | @ TB | Sunday 1:00 PM | |
| 53 | QB Tim Boyle | + 0 | @ CHI | Sunday 8:20 PM | |
| 54 | QB Joe Flacco | + 0 | @ NE | Sunday 1:00 PM | |
| 55 | QB Case Keenum | + 0 | vs PIT | Sunday 1:00 PM | |
| 56 | QB Geno Smith | + 0 | @ SF | Sunday 4:05 PM | |
| 57 | QB Nate Sudfeld | + 0 | vs WAS | Monday 8:15 PM | |
| 58 | QB Sean Mannion | + 0 | @ DET | Sunday 1:00 PM | |
| 59 | QB David Blough | + 0 | vs MIN | Thursday 12:30 PM | |
| 60 | QB Brett Rypien | + 0 | vs LV | Sunday 4:05 PM | |
| 61 | QB Tyler Huntley | + 0 | @ CIN | Sunday 1:00 PM | |
| 62 | QB AJ McCarron | + 0 | vs TEN | Sunday 1:00 PM | |
| 63 | QB Logan Woodside | + 0 | @ HOU | Sunday 1:00 PM | |
| 64 | QB Chris Streveler | + 0 | @ LAR | Sunday 4:05 PM |